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CRISPR/Cas9 Genome-Editing System in Human Stem Cells: Current Status and Future Prospects
Genome-editing involves the insertion, deletion, or replacement of DNA in the genome of a living organism using “molecular scissors.” Traditional genome editing with engineered nucleases for human stem cells is limited by its low efficiency, high cost, and poor specificity. The CRISPR system has rec...
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| Pubblicato in: | Mol Ther Nucleic Acids |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Gene & Cell Therapy
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5651489/ https://ncbi.nlm.nih.gov/pubmed/29246302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.09.009 |
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