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Structure of the Mitochondrial Translocator Protein in Complex with a Diagnostic Ligand

The 18 kDa translocator protein (TSPO) is found in mitochondrial membranes and mediates the import of cholesterol and porphyrins into mitochondria. In line with the role of TSPO in mitochondrial function, TSPO ligands are used for a variety of diagnostic and therapeutic applications in animals and h...

詳細記述

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書誌詳細
出版年:Science
主要な著者: Jaremko, Łukasz, Jaremko, Mariusz, Giller, Karin, Becker, Stefan, Zweckstetter, Markus
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650047/
https://ncbi.nlm.nih.gov/pubmed/24653034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1248725
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