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Conformational Flexibility in the Transmembrane Protein TSPO

The translocator protein TSPO is an integral membrane protein that interacts with a large variety of endogenous ligands such as cholesterol and porphyrins, and is also the target for several small molecules with substantial in vivo efficacy. In complex with the TSPO-specific radioligand (R)-PK11195,...

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Bibliografski detalji
Izdano u:Chemistry
Glavni autori: Jaremko, Łukasz, Jaremko, Mariusz, Giller, Karin, Becker, Stefan, Zweckstetter, Markus
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654506/
https://ncbi.nlm.nih.gov/pubmed/26394723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201502314
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