Structural integrity of the A147T polymorph of mammalian TSPO

Ligands of the transmembrane protein TSPO are used for imaging of brain inflammation, but a common polymorphism in TSPO complicates their application to humans. Here we determined the three-dimensional structure and side chain dynamics of the A147T polymorph of mammalian TSPO in complex with the fir...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Chembiochem
Asıl Yazarlar: Jaremko, Mariusz, Jaremko, Łukasz, Giller, Karin, Becker, Stefan, Zweckstetter, Markus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653209/
https://ncbi.nlm.nih.gov/pubmed/25974690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500217
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