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Structural integrity of the A147T polymorph of mammalian TSPO
Ligands of the transmembrane protein TSPO are used for imaging of brain inflammation, but a common polymorphism in TSPO complicates their application to humans. Here we determined the three-dimensional structure and side chain dynamics of the A147T polymorph of mammalian TSPO in complex with the fir...
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| Publicat a: | Chembiochem |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5653209/ https://ncbi.nlm.nih.gov/pubmed/25974690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500217 |
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