Cholesterol-mediated allosteric regulation of the mitochondrial translocator protein structure

Cholesterol is an important regulator of membrane protein function. However, the exact mechanisms involved in this process are still not fully understood. Here we study how the tertiary and quaternary structure of the mitochondrial translocator protein TSPO, which binds cholesterol with nanomolar af...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Jaipuria, Garima, Leonov, Andrei, Giller, Karin, Vasa, Suresh Kumar, Jaremko, Łukasz, Jaremko, Mariusz, Linser, Rasmus, Becker, Stefan, Zweckstetter, Markus
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379104/
https://ncbi.nlm.nih.gov/pubmed/28358007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14893
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg