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Cholesterol-mediated allosteric regulation of the mitochondrial translocator protein structure

Cholesterol is an important regulator of membrane protein function. However, the exact mechanisms involved in this process are still not fully understood. Here we study how the tertiary and quaternary structure of the mitochondrial translocator protein TSPO, which binds cholesterol with nanomolar af...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Jaipuria, Garima, Leonov, Andrei, Giller, Karin, Vasa, Suresh Kumar, Jaremko, Łukasz, Jaremko, Mariusz, Linser, Rasmus, Becker, Stefan, Zweckstetter, Markus
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379104/
https://ncbi.nlm.nih.gov/pubmed/28358007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14893
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