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Cholesterol-mediated allosteric regulation of the mitochondrial translocator protein structure
Cholesterol is an important regulator of membrane protein function. However, the exact mechanisms involved in this process are still not fully understood. Here we study how the tertiary and quaternary structure of the mitochondrial translocator protein TSPO, which binds cholesterol with nanomolar af...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5379104/ https://ncbi.nlm.nih.gov/pubmed/28358007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14893 |
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