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Cholesterol-mediated allosteric regulation of the mitochondrial translocator protein structure
Cholesterol is an important regulator of membrane protein function. However, the exact mechanisms involved in this process are still not fully understood. Here we study how the tertiary and quaternary structure of the mitochondrial translocator protein TSPO, which binds cholesterol with nanomolar af...
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| Gepubliceerd in: | Nat Commun |
|---|---|
| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5379104/ https://ncbi.nlm.nih.gov/pubmed/28358007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14893 |
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