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Structure of the Mitochondrial Translocator Protein in Complex with a Diagnostic Ligand
The 18 kDa translocator protein (TSPO) is found in mitochondrial membranes and mediates the import of cholesterol and porphyrins into mitochondria. In line with the role of TSPO in mitochondrial function, TSPO ligands are used for a variety of diagnostic and therapeutic applications in animals and h...
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| Pubblicato in: | Science |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5650047/ https://ncbi.nlm.nih.gov/pubmed/24653034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1248725 |
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