Llwytho...
Evolutionary drivers of thermoadaptation in enzyme catalysis
With early life likely to have existed in a hot environment, enzymes had to cope with an inherent drop in catalytic speed caused by lowered temperature. Here we characterize the molecular mechanisms underlying thermoadaptation of enzyme catalysis in adenylate kinase using ancestral sequence reconstr...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Science |
|---|---|
| Prif Awduron: | , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5649376/ https://ncbi.nlm.nih.gov/pubmed/28008087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aah3717 |
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