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Evolution and intelligent design in drug development

Sophisticated protein kinase networks, empowering complexity in higher organisms, are also drivers of devastating diseases such as cancer. Accordingly, these enzymes have become major drug targets of the twenty-first century. However, the holy grail of designing specific kinase inhibitors aimed at s...

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Detalles Bibliográficos
Publicado en:Front Mol Biosci
Autores principales: Agafonov, Roman V., Wilson, Christopher, Kern, Dorothee
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440380/
https://ncbi.nlm.nih.gov/pubmed/26052517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2015.00027
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