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The dock-and-coalesce mechanism for the association of a WASP disordered region with the Cdc42 GTPase

Intrinsically disordered proteins (IDPs) play key roles in signaling and regulation. Many IDPs undergo folding upon binding to their targets. We have proposed that coupled folding and binding of IDPs generally follow a dock-and-coalesce mechanism, whereby a segment of the IDP, through diffusion, doc...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FEBS J
Egile Nagusiak: Ou, Li, Matthews, Megan, Pang, Xiaodong, Zhou, Huan-Xiang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643242/
https://ncbi.nlm.nih.gov/pubmed/28805312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14197
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