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Allosteric activation of SENP1 by SUMO1 β-grasp domain involves a dock-and-coalesce mechanism
Small ubiquitin-related modifiers (SUMOs) are conjugated to proteins to regulate a variety of cellular processes. SENPs are cysteine proteases with a catalytic center located within a channel between two subdomains that catalyzes SUMO C-terminal cleavage for processing of SUMO precursors and de-SUMO...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5030089/ https://ncbi.nlm.nih.gov/pubmed/27576863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18249 |
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