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The dock-and-coalesce mechanism for the association of a WASP disordered region with the Cdc42 GTPase

Intrinsically disordered proteins (IDPs) play key roles in signaling and regulation. Many IDPs undergo folding upon binding to their targets. We have proposed that coupled folding and binding of IDPs generally follow a dock-and-coalesce mechanism, whereby a segment of the IDP, through diffusion, doc...

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Podrobná bibliografie
Vydáno v:FEBS J
Hlavní autoři: Ou, Li, Matthews, Megan, Pang, Xiaodong, Zhou, Huan-Xiang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643242/
https://ncbi.nlm.nih.gov/pubmed/28805312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14197
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