A carregar...
Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase
Human farnesyl pyrophosphate synthase (hFPPS) catalyzes the production of the 15-carbon isoprenoid farnesyl pyrophosphate. The enzyme is a key regulator of the mevalonate pathway and a well-established drug target. Notably, it was elucidated as the molecular target of nitrogen-containing bisphosphon...
Na minha lista:
| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5643135/ https://ncbi.nlm.nih.gov/pubmed/29036218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186447 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|