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Human isoprenoid synthase enzymes as therapeutic targets

In the human body, the complex biochemical network known as the mevalonate pathway is responsible for the biosynthesis of all isoprenoids, which consists of a vast array of metabolites that are vital for proper cellular functions. Two key isoprenoids, farnesyl pyrophosphate (FPP) and geranylgeranyl...

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Main Authors: Park, Jaeok, Matralis, Alexios N., Berghuis, Albert M., Tsantrizos, Youla S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106277/
https://ncbi.nlm.nih.gov/pubmed/25101260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2014.00050
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