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Human isoprenoid synthase enzymes as therapeutic targets

In the human body, the complex biochemical network known as the mevalonate pathway is responsible for the biosynthesis of all isoprenoids, which consists of a vast array of metabolites that are vital for proper cellular functions. Two key isoprenoids, farnesyl pyrophosphate (FPP) and geranylgeranyl...

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Detalhes bibliográficos
Main Authors: Park, Jaeok, Matralis, Alexios N., Berghuis, Albert M., Tsantrizos, Youla S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106277/
https://ncbi.nlm.nih.gov/pubmed/25101260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2014.00050
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