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Pharmaceutical Analysis of a Novel Propargyl-linked Antifolate Antibiotic in the Mouse

Antimicrobial resistance to current antibiotics is a significant public health problem and the need for new antibiotics is a compelling one. We have been developing a new series of antibiotics, propargyl-linked diaminopyrimidines, based on the structure of trimethoprim. To date we have discovered co...

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Vydáno v:J Chromatogr B Analyt Technol Biomed Life Sci
Hlavní autoři: Hoody, John, Alverson, Jeremy B., Keshipeddy, Santosh, Barney, Patrick A., Walker, Larissa, Anderson, Amy C., Wright, Dennis L., Priestley, Nigel D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635995/
https://ncbi.nlm.nih.gov/pubmed/28314188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2017.02.026
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