Laddar...

The DEAD-box protein Dhh1p couples mRNA decay and translation by monitoring codon optimality

A major determinant of mRNA half-life is the codon-dependent rate of translational elongation. How the processes of translational elongation and mRNA decay communicate is unclear. Here we establish that the DEAD-box protein Dhh1p is a sensor of codon optimality that targets an mRNA for decay. First,...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Cell
Huvudupphovsmän: Radhakrishnan, Aditya, Chen, Ying-Hsin, Martin, Sophie, Alhusaini, Najwa, Green, Rachel, Coller, Jeff
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635654/
https://ncbi.nlm.nih.gov/pubmed/27641505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.08.053
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!