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The DEAD-Box Protein Dhh1 Promotes Decapping by Slowing Ribosome Movement

Translational control and messenger RNA (mRNA) decay represent important control points in the regulation of gene expression. In yeast, the major pathway for mRNA decay is initiated by deadenylation followed by decapping and 5′–3′ exonucleolytic digestion of the mRNA. Proteins that activate decappin...

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Detalhes bibliográficos
Main Authors: Sweet, Thomas, Kovalak, Carrie, Coller, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373615/
https://ncbi.nlm.nih.gov/pubmed/22719226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001342
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