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Tumor-targeted costimulation by using bi-specific aptamers

Aptamers are chemically synthesized oligonucleotides that can be easily engineered for cancer immunotherapy use. So far, most of the therapeutic aptamers described are antagonistic and block the function of a receptor or its soluble ligand. Recently, aptamers have been modified to act as agonists by...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Cell Microenviron
Prif Awdur: Pastor, Fernando
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627702/
https://ncbi.nlm.nih.gov/pubmed/28989946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14800/ccm.1333
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