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Tumor-targeted costimulation by using bi-specific aptamers

Aptamers are chemically synthesized oligonucleotides that can be easily engineered for cancer immunotherapy use. So far, most of the therapeutic aptamers described are antagonistic and block the function of a receptor or its soluble ligand. Recently, aptamers have been modified to act as agonists by...

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Библиографические подробности
Опубликовано в: :Cancer Cell Microenviron
Главный автор: Pastor, Fernando
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627702/
https://ncbi.nlm.nih.gov/pubmed/28989946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14800/ccm.1333
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