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Tumor-targeted costimulation by using bi-specific aptamers

Aptamers are chemically synthesized oligonucleotides that can be easily engineered for cancer immunotherapy use. So far, most of the therapeutic aptamers described are antagonistic and block the function of a receptor or its soluble ligand. Recently, aptamers have been modified to act as agonists by...

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Detalhes bibliográficos
Publicado no:Cancer Cell Microenviron
Autor principal: Pastor, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627702/
https://ncbi.nlm.nih.gov/pubmed/28989946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14800/ccm.1333
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