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Bi-specific Aptamers Mediating Tumor Cell Lysis

Antibody-dependent cellular cytotoxicity plays a pivotal role in antibody-based tumor therapies and is based on the recruitment of natural killer cells to antibody-bound tumor cells via binding of the Fcγ receptor III (CD16). Here we describe the generation of chimeric DNA aptamers that simultaneous...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Boltz, Achim, Piater, Birgit, Toleikis, Lars, Guenther, Ralf, Kolmar, Harald, Hock, Bjoern
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122244/
https://ncbi.nlm.nih.gov/pubmed/21531729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.238261
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