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Bi-specific Aptamers Mediating Tumor Cell Lysis
Antibody-dependent cellular cytotoxicity plays a pivotal role in antibody-based tumor therapies and is based on the recruitment of natural killer cells to antibody-bound tumor cells via binding of the Fcγ receptor III (CD16). Here we describe the generation of chimeric DNA aptamers that simultaneous...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122244/ https://ncbi.nlm.nih.gov/pubmed/21531729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.238261 |
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