Epithelial Chloride Transport by CFTR Requires TMEM16A

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is the secretory chloride/bicarbonate channel in airways and intestine that is activated through ATP binding and phosphorylation by protein kinase A, but fails to operate in cystic fibrosis (CF). TMEM16A (also known as anoctamin 1, ANO1) is...

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Publicat a:Sci Rep
Autors principals: Benedetto, Roberta, Ousingsawat, Jiraporn, Wanitchakool, Podchanart, Zhang, Yong, Holtzman, Michael J., Amaral, Margarida, Rock, Jason R., Schreiber, Rainer, Kunzelmann, Karl
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622110/
https://ncbi.nlm.nih.gov/pubmed/28963502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10910-0
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