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TMEM16 Proteins Produce Volume-regulated Chloride Currents That Are Reduced in Mice Lacking TMEM16A

All vertebrate cells regulate their cell volume by activating chloride channels of unknown molecular identity, thereby activating regulatory volume decrease. We show that the Ca(2+)-activated Cl(−) channel TMEM16A together with other TMEM16 proteins are activated by cell swelling through an autocrin...

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Detalhes bibliográficos
Main Authors: Almaça, Joana, Tian, Yuemin, Aldehni, Fadi, Ousingsawat, Jiraporn, Kongsuphol, Patthara, Rock, Jason R., Harfe, Brian D., Schreiber, Rainer, Kunzelmann, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781400/
https://ncbi.nlm.nih.gov/pubmed/19654323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.010074
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