TMEM16 Proteins Produce Volume-regulated Chloride Currents That Are Reduced in Mice Lacking TMEM16A

All vertebrate cells regulate their cell volume by activating chloride channels of unknown molecular identity, thereby activating regulatory volume decrease. We show that the Ca(2+)-activated Cl(−) channel TMEM16A together with other TMEM16 proteins are activated by cell swelling through an autocrin...

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Bibliografski detalji
Glavni autori: Almaça, Joana, Tian, Yuemin, Aldehni, Fadi, Ousingsawat, Jiraporn, Kongsuphol, Patthara, Rock, Jason R., Harfe, Brian D., Schreiber, Rainer, Kunzelmann, Karl
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Membrane Transport, Structure, Function, and Biogenesis
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781400/
https://ncbi.nlm.nih.gov/pubmed/19654323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.010074
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