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Loss of TMEM16A Causes a Defect in Epithelial Ca(2+)-dependent Chloride Transport

Molecular identification of the Ca(2+)-dependent chloride channel TMEM16A (ANO1) provided a fundamental step in understanding Ca(2+)-dependent Cl(−) secretion in epithelia. TMEM16A is an intrinsic constituent of Ca(2+)-dependent Cl(−) channels in cultured epithelia and may control salivary output, b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ousingsawat, Jiraporn, Martins, Joana R., Schreiber, Rainer, Rock, Jason R., Harfe, Brian D., Kunzelmann, Karl
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781414/
https://ncbi.nlm.nih.gov/pubmed/19679661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.012120
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