Epithelial Chloride Transport by CFTR Requires TMEM16A

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is the secretory chloride/bicarbonate channel in airways and intestine that is activated through ATP binding and phosphorylation by protein kinase A, but fails to operate in cystic fibrosis (CF). TMEM16A (also known as anoctamin 1, ANO1) is...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Benedetto, Roberta, Ousingsawat, Jiraporn, Wanitchakool, Podchanart, Zhang, Yong, Holtzman, Michael J., Amaral, Margarida, Rock, Jason R., Schreiber, Rainer, Kunzelmann, Karl
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622110/
https://ncbi.nlm.nih.gov/pubmed/28963502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10910-0
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