Epithelial Chloride Transport by CFTR Requires TMEM16A

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is the secretory chloride/bicarbonate channel in airways and intestine that is activated through ATP binding and phosphorylation by protein kinase A, but fails to operate in cystic fibrosis (CF). TMEM16A (also known as anoctamin 1, ANO1) is...

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Publicado no:Sci Rep
Main Authors: Benedetto, Roberta, Ousingsawat, Jiraporn, Wanitchakool, Podchanart, Zhang, Yong, Holtzman, Michael J., Amaral, Margarida, Rock, Jason R., Schreiber, Rainer, Kunzelmann, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5622110/
https://ncbi.nlm.nih.gov/pubmed/28963502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10910-0
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