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Regulation of TMEM16A/ANO1 and TMEM16F/ANO6 ion currents and phospholipid scrambling by Ca(2+) and plasma membrane lipid
KEY POINTS: TMEM16 proteins can operate as Ca(2+)‐activated Cl(−) channels or scramble membrane phospholipids, which are both highly relevant mechanisms during disease. Overexpression of TMEM16A and TMEM16F were found to be partially active at 37°C and at resting intracellular Ca(2+) concentrations....
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| Publicado en: | J Physiol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5767690/ https://ncbi.nlm.nih.gov/pubmed/29134661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275175 |
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