Inhibition of NADPH oxidase 2 (NOX2) prevents sepsis-induced cardiomyopathy by improving calcium handling and mitochondrial function

Cardiomyopathy frequently complicates sepsis and is associated with increased mortality. Increased cardiac oxidative stress and mitochondrial dysfunction have been observed during sepsis, but the mechanisms responsible for these abnormalities have not been determined. We hypothesized that NADPH oxid...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:JCI Insight
मुख्य लेखकों: Joseph, Leroy C., Kokkinaki, Dimitra, Valenti, Mesele-Christina, Kim, Grace J., Barca, Emanuele, Tomar, Dhanendra, Hoffman, Nicholas E., Subramanyam, Prakash, Colecraft, Henry M., Hirano, Michio, Ratner, Adam J., Madesh, Muniswamy, Drosatos, Konstantinos, Morrow, John P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2017
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621873/
https://ncbi.nlm.nih.gov/pubmed/28878116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94248
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन