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The Role of the NADPH Oxidase NOX2 in Prion Pathogenesis
Prion infections cause neurodegeneration, which often goes along with oxidative stress. However, the cellular source of reactive oxygen species (ROS) and their pathogenetic significance are unclear. Here we analyzed the contribution of NOX2, a prominent NADPH oxidase, to prion diseases. We found tha...
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| Publicado en: | PLoS Pathog |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4263757/ https://ncbi.nlm.nih.gov/pubmed/25502554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004531 |
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