The Role of the NADPH Oxidase NOX2 in Prion Pathogenesis

Prion infections cause neurodegeneration, which often goes along with oxidative stress. However, the cellular source of reactive oxygen species (ROS) and their pathogenetic significance are unclear. Here we analyzed the contribution of NOX2, a prominent NADPH oxidase, to prion diseases. We found tha...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: Sorce, Silvia, Nuvolone, Mario, Keller, Annika, Falsig, Jeppe, Varol, Ahmet, Schwarz, Petra, Bieri, Monika, Budka, Herbert, Aguzzi, Adriano
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263757/
https://ncbi.nlm.nih.gov/pubmed/25502554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004531
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