Structure of the forkhead domain of FOXA2 bound to a complete DNA consensus site

FOXA2, a member of the forkhead family of transcription factors, plays essential roles in liver development and bile acid homeostasis. In this study, we report a 2.8 Å co-crystal structure of the FOXA2 DNA-binding domain (FOXA2-DBD) bound to a DNA duplex containing a forkhead consensus binding site...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Li, Jun, Machado, Ana Carolina Dantas, Guo, Ming, Sagendorf, Jared M., Zhou, Zhan, Jiang, Longying, Chen, Xiaojuan, Wu, Daichao, Qu, Lingzhi, Chen, Zhuchu, Chen, Lin, Rohs, Remo, Chen, Yongheng
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614898/
https://ncbi.nlm.nih.gov/pubmed/28644006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00211
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki