Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface

MEF2 and NKX2-5 transcription factors interact with each other in cardiogenesis and are necessary for normal heart formation. Despite evidence suggesting that these two transcription factors function synergistically and possibly through direct physical interactions, molecular mechanisms by which the...

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Publicado no:J Mol Biol
Main Authors: Lei, Xiao, Zhao, Jun, Sagendorf, Jared M., Rajashekar, Niroop, Xu, Jiang, Machado, Ana Carolina Dantas, Sen, Chandani, Rohs, Remo, Feng, Pinghui, Chen, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099449/
https://ncbi.nlm.nih.gov/pubmed/32681840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.07.004
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