Mechanism of forkhead transcription factors binding to a novel palindromic DNA site

Forkhead transcription factors bind a canonical consensus DNA motif, RYAAAYA (R = A/G, Y = C/T), as a monomer. However, the molecular mechanisms by which forkhead transcription factors bind DNA as a dimer are not well understood. In this study, we show that FOXO1 recognizes a palindromic DNA element...

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Li, Jun, Dai, Shuyan, Chen, Xiaojuan, Liang, Xujun, Qu, Lingzhi, Jiang, Longying, Guo, Ming, Zhou, Zhan, Wei, Hudie, Zhang, Huajun, Chen, Zhuchu, Chen, Lin, Chen, Yongheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Structural Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034652/
https://ncbi.nlm.nih.gov/pubmed/33577686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab086
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