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Structural basis for DNA recognition by FOXC2

The FOXC family of transcription factors (FOXC1 and FOXC2) plays essential roles in the regulation of embryonic, ocular, and cardiac development. Mutations and abnormal expression of FOXC proteins are implicated in genetic diseases as well as cancer. In this study, we determined two crystal structur...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Chen, Xiaojuan, Wei, Hudie, Li, Jun, Liang, Xujun, Dai, Shuyan, Jiang, Longying, Guo, Ming, Qu, Lingzhi, Chen, Zhuchu, Chen, Lin, Chen, Yongheng
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468292/
https://ncbi.nlm.nih.gov/pubmed/30722065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz077
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