Structural basis for DNA recognition by FOXC2

The FOXC family of transcription factors (FOXC1 and FOXC2) plays essential roles in the regulation of embryonic, ocular, and cardiac development. Mutations and abnormal expression of FOXC proteins are implicated in genetic diseases as well as cancer. In this study, we determined two crystal structur...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Chen, Xiaojuan, Wei, Hudie, Li, Jun, Liang, Xujun, Dai, Shuyan, Jiang, Longying, Guo, Ming, Qu, Lingzhi, Chen, Zhuchu, Chen, Lin, Chen, Yongheng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2019
Pynciau:
Structural Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468292/
https://ncbi.nlm.nih.gov/pubmed/30722065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz077
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