Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis

The tumor suppressor p53 is mutated in approximately half of all human cancers. p53 can induce apoptosis through mitochondrial membrane permeabilization by interacting with and antagonizing the anti-apoptotic proteins BCL-xL and BCL-2. However, the mechanisms by which p53 induces mitochondrial apopt...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Wei, Hudie, Qu, Lingzhi, Dai, Shuyan, Li, Yun, Wang, Haolan, Feng, Yilu, Chen, Xiaojuan, Jiang, Longying, Guo, Ming, Li, Jun, Chen, Zhuchu, Chen, Lin, Zhang, Ye, Chen, Yongheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052441/
https://ncbi.nlm.nih.gov/pubmed/33863900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22655-6
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items