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Structural basis of binding of homodimers of the nuclear receptor NR4A2 to selective Nur-responsive DNA elements
Proteins of nuclear receptor subfamily 4 group A (NR4A), including NR4A1/NGFI-B, NR4A2/Nurr1, and NR4A3/NOR-1, are nuclear transcription factors that play important roles in metabolism, apoptosis, and proliferation. NR4A proteins recognize DNA response elements as monomers or dimers to regulate the...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6926456/ https://ncbi.nlm.nih.gov/pubmed/31723028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010730 |
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