Structural basis of binding of homodimers of the nuclear receptor NR4A2 to selective Nur-responsive DNA elements

Proteins of nuclear receptor subfamily 4 group A (NR4A), including NR4A1/NGFI-B, NR4A2/Nurr1, and NR4A3/NOR-1, are nuclear transcription factors that play important roles in metabolism, apoptosis, and proliferation. NR4A proteins recognize DNA response elements as monomers or dimers to regulate the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Jiang, Longying, Dai, Shuyan, Li, Jun, Liang, Xujun, Qu, Lingzhi, Chen, Xiaojuan, Guo, Ming, Chen, Zhuchu, Chen, Lin, Wei, Hudie, Chen, Yongheng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2019
Pynciau:
Protein Structure and Folding
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926456/
https://ncbi.nlm.nih.gov/pubmed/31723028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010730
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