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Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Traditional pharmaceutical drug discovery is almost exclusively focused on directly controlling protein activity to cure diseases. Modulators of protein activity, especially inhibitors, are developed and applied at high concentration to achieve maximal effects. Thereby, reduced bioavailability and o...
Tallennettuna:
| Julkaisussa: | Cell Chem Biol |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5610075/ https://ncbi.nlm.nih.gov/pubmed/28648379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.05.024 |
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