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Chemical Inducers of Targeted Protein Degradation
The functions of many cellular proteins have been elucidated by selective gene inactivation and subsequent phenotypic analysis. For example, genetic mutations, gene knock-out generation, and the use of RNA interference to target mRNA for degradation can all result in decreased production of a specif...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856979/ https://ncbi.nlm.nih.gov/pubmed/20147751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R109.078105 |
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