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Targeted Protein Knockdown using Small Molecule Degraders
Small molecule probes of biological systems have traditionally been designed to bind to and inhibit the active sites of their protein targets. While this class of pharmacological agents has been broadened by the development of a small number of allosteric and protein-protein interaction (PPI) inhibi...
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| Publicado no: | Curr Opin Chem Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584562/ https://ncbi.nlm.nih.gov/pubmed/28605671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2017.05.016 |
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