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Targeted Protein Knockdown using Small Molecule Degraders
Small molecule probes of biological systems have traditionally been designed to bind to and inhibit the active sites of their protein targets. While this class of pharmacological agents has been broadened by the development of a small number of allosteric and protein-protein interaction (PPI) inhibi...
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| Veröffentlicht in: | Curr Opin Chem Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584562/ https://ncbi.nlm.nih.gov/pubmed/28605671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2017.05.016 |
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