Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi

Deep penetrating nevus (DPN) is characterized by enlarged, pigmented melanocytes that extend through the dermis. DPN can be difficult to distinguish from melanoma but rarely displays aggressive biological behavior. Here, we identify a combination of mutations of the β-catenin and mitogen-activated p...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Yeh, Iwei, Lang, Ursula E., Durieux, Emeline, Tee, Meng Kian, Jorapur, Aparna, Shain, A. Hunter, Haddad, Veronique, Pissaloux, Daniel, Chen, Xu, Cerroni, Lorenzo, Judson, Robert L., LeBoit, Philip E., McCalmont, Timothy H., Bastian, Boris C., de la Fouchardière, Arnaud
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608693/
https://ncbi.nlm.nih.gov/pubmed/28935960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00758-3
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki