Clinical, Histopathologic and Genomic Features of Spitz Tumors with ALK Fusions

Activating kinase fusions have recently been described as early oncogenic events that are mutually exclusive with HRAS and BRAF mutations in Spitz tumors. Here, we report a series of 32 Spitz tumors with ALK fusions (6 Spitz nevi, 22 atypical Spitz tumors, and 4 Spitzoid melanomas) in patients rangi...

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Pubblicato in:Am J Surg Pathol
Autori principali: Yeh, Iwei, de la Fouchardiere, Arnaud, Pissaloux, Daniel, Mully, Thaddeus W., Garrido, Maria C., Vemula, Swapna S., Busam, Klaus J., LeBoit, Philip E., McCalmont, Timothy H., Bastian, Boris C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398593/
https://ncbi.nlm.nih.gov/pubmed/25602801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000387
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