Clinical, Histopathologic and Genomic Features of Spitz Tumors with ALK Fusions

Activating kinase fusions have recently been described as early oncogenic events that are mutually exclusive with HRAS and BRAF mutations in Spitz tumors. Here, we report a series of 32 Spitz tumors with ALK fusions (6 Spitz nevi, 22 atypical Spitz tumors, and 4 Spitzoid melanomas) in patients rangi...

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Veröffentlicht in:Am J Surg Pathol
Hauptverfasser: Yeh, Iwei, de la Fouchardiere, Arnaud, Pissaloux, Daniel, Mully, Thaddeus W., Garrido, Maria C., Vemula, Swapna S., Busam, Klaus J., LeBoit, Philip E., McCalmont, Timothy H., Bastian, Boris C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398593/
https://ncbi.nlm.nih.gov/pubmed/25602801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000387
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