Activating MET Kinase Rearrangements in Melanoma and Spitz Tumors

Oncogenic gene fusions have been identified in many cancers and many serve as biomarkers or targets for therapy. Here we identify six different melanocytic tumors with genomic rearrangements of MET fusing the kinase domain of MET in-frame to six different N-terminal partners. These tumors lack activ...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yeh, Iwei, Botton, Thomas, Talevich, Eric, Shain, A. Hunter, Sparatta, Alyssa J., de la Fouchardiere, Arnaud, Mully, Thaddeus W., North, Jeffrey P., Garrido, Maria C., Gagnon, Alexander, Vemula, Swapna S., McCalmont, Timothy H., LeBoit, Philip E., Bastian, Boris C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446791/
https://ncbi.nlm.nih.gov/pubmed/26013381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8174
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados