NTRK3 kinase fusions in Spitz tumours

Oncogenic fusions in TRK family receptor tyrosine kinases have been identified in several cancers and can serve as therapeutic targets. We identified ETV6-NTRK3, MYO5A-NTRK3 and MYH9-NTRK3 fusions in Spitz tumours and demonstrate that NTRK3 fusions constitutively activate the MAPK, PI3K and PLCγ1 pa...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Pathol
मुख्य लेखकों: Yeh, Iwei, Tee, Meng Kian, Botton, Thomas, Shain, A. Hunter, Sparatta, Alyssa J., Gagnon, Alexander, Vemula, Swapna S., Garrido, Maria C., Nakamaru, Kenji, Isoyama, Takeshi, McCalmont, Timothy H., LeBoit, Philip E., Bastian, Boris C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071153/
https://ncbi.nlm.nih.gov/pubmed/27477320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4775
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