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NTRK3 kinase fusions in Spitz tumours
Oncogenic fusions in TRK family receptor tyrosine kinases have been identified in several cancers and can serve as therapeutic targets. We identified ETV6-NTRK3, MYO5A-NTRK3 and MYH9-NTRK3 fusions in Spitz tumours and demonstrate that NTRK3 fusions constitutively activate the MAPK, PI3K and PLCγ1 pa...
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| Publicat a: | J Pathol |
|---|---|
| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5071153/ https://ncbi.nlm.nih.gov/pubmed/27477320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4775 |
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