Combined activation of MAP kinase pathway and β-catenin signaling cause deep penetrating nevi

Deep penetrating nevus (DPN) is characterized by enlarged, pigmented melanocytes that extend through the dermis. DPN can be difficult to distinguish from melanoma but rarely displays aggressive biological behavior. Here, we identify a combination of mutations of the β-catenin and mitogen-activated p...

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Publicado no:Nat Commun
Main Authors: Yeh, Iwei, Lang, Ursula E., Durieux, Emeline, Tee, Meng Kian, Jorapur, Aparna, Shain, A. Hunter, Haddad, Veronique, Pissaloux, Daniel, Chen, Xu, Cerroni, Lorenzo, Judson, Robert L., LeBoit, Philip E., McCalmont, Timothy H., Bastian, Boris C., de la Fouchardière, Arnaud
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5608693/
https://ncbi.nlm.nih.gov/pubmed/28935960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00758-3
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