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Potentiation of Hydrogen Peroxide Toxicity: From Catalase Inhibition to Stable DNA-iron Complexes
Hydrogen peroxide (H(2)O(2)) is unique among general toxins, because it is stable in abiotic environments at ambient temperature and neutral pH, yet rapidly kills any type of cells by producing highly-reactive hydroxyl radicals. This life-specific reactivity follows distribution of soluble iron, Fe(...
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| Veröffentlicht in: | Mutat Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5607474/ https://ncbi.nlm.nih.gov/pubmed/28927535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2016.08.006 |
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