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Potentiation of Hydrogen Peroxide Toxicity: From Catalase Inhibition to Stable DNA-iron Complexes

Hydrogen peroxide (H(2)O(2)) is unique among general toxins, because it is stable in abiotic environments at ambient temperature and neutral pH, yet rapidly kills any type of cells by producing highly-reactive hydroxyl radicals. This life-specific reactivity follows distribution of soluble iron, Fe(...

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Bibliografski detalji
Izdano u:Mutat Res
Glavni autori: Mahaseth, Tulip, Kuzminov, Andrei
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607474/
https://ncbi.nlm.nih.gov/pubmed/28927535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2016.08.006
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