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Potentiation of Hydrogen Peroxide Toxicity: From Catalase Inhibition to Stable DNA-iron Complexes

Hydrogen peroxide (H(2)O(2)) is unique among general toxins, because it is stable in abiotic environments at ambient temperature and neutral pH, yet rapidly kills any type of cells by producing highly-reactive hydroxyl radicals. This life-specific reactivity follows distribution of soluble iron, Fe(...

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Detalhes bibliográficos
Publicado no:Mutat Res
Main Authors: Mahaseth, Tulip, Kuzminov, Andrei
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5607474/
https://ncbi.nlm.nih.gov/pubmed/28927535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2016.08.006
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