Cargando...

Prompt repair of hydrogen peroxide-induced DNA lesions prevents catastrophic chromosomal fragmentation

Iron-dependent oxidative DNA damage in vivo by hydrogen peroxide (H(2)O(2), HP) induces copious single-strand(ss)-breaks and base modifications. HP also causes infrequent double-strand DNA breaks, whose relationship to the cell killing is unclear. Since hydrogen peroxide only fragments chromosomes i...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:DNA Repair (Amst)
Main Authors: Mahaseth, Tulip, Kuzminov, Andrei
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851570/
https://ncbi.nlm.nih.gov/pubmed/27078578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.03.012
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!